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Editorial Board
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IFC
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| Introduction to Symposium |
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Introduction to Symposium
For millennia, wine and other alcoholic beverages have been associated with health and for centuries were a part of the physician's pharmacopoeia. During the late 19th and early 20th centuries, the pu...
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R. Curtis Ellison
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S1-S2
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| I. Moderate Drinking and Cardiovascular Disease |
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Alcohol and Coronary Heart Disease: Drinking Patterns and Mediators of Effect
An inverse association between alcohol consumption and coronary heart disease (CHD) has been shown in epidemiologic studies for more than 30 years; beneficial changes in high-density lipoprotein (HDL)...
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Eric B. Rimm,
Caroline Moats
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S3-S7
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Alcohol Intake and Noncoronary Cardiovascular Diseases
Moderate drinking has complex associations with cardiovascular diseases other than coronary heart disease. Recent cohort studies examining the relationship between alcohol use and ischemic stroke have...
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Kenneth Mukamal
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S8-S12
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Confounders of the Relation between Type of Alcohol and Cardiovascular Disease
There have been numerous reports from epidemiologic studies showing that moderate drinkers have lower rates of cardiovascular disease (CVD) than do those who drink heavily or not at all. A number of s...
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Morten Grønbæk
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S13-S15
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Moderate Alcohol Use and Reduced Mortality Risk: Systematic Error in Prospective Studies and New Hypotheses
We have provided recent evidence suggesting that a systematic error may be operating in prospective epidemiological mortality studies that have reported “light” or “moderate” regular use of alcohol to...
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Kaye Middleton Fillmore,
Tim Stockwell,
Tanya Chikritzhs,
Alan Bostrom,
William Kerr
et al.
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S16-S23
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Mechanism by which Alcohol and Wine Polyphenols Affect Coronary Heart Disease Risk
The reduction in coronary heart disease (CHD) from moderate alcohol intake may be mediated, in part, by increased fibrinolysis; endothelial cell (EC)–mediated fibrinolysis should decrease acute athero...
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Francois M. Booyse,
Wensheng Pan,
Hernan E. Grenett,
Dale A. Parks,
Victor M. Darley-Usmar,
Kelley M. Bradley,
Edlue M. Tabengwa
et al.
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S24-S31
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Changes in Cardiovascular Risk Factors Associated with Wine Consumption in Intervention Studies in Humans
Evidence that links moderate wine consumption to cardiovascular health corresponds mostly to ecological observations. Intervention studies using moderate wine consumption with ischemic heart disease a...
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Federico Leighton,
Inés Urquiaga
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S32-S36
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Panel Discussion I: Does Alcohol Consumption Prevent Cardiovascular Disease?
The panel on the relationship between alcohol consumption and cardiovascular disease was chaired by R. Curtis Ellison and the panelists were Goya Wannamethee, Eric B. Rimm, Kenneth J. Mukamal, Morten ...
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S37-S39
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| II. Moderate Drinking and Other Health Outcomes |
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Moderate Alcohol Consumption and Insulin Sensitivity: Observations and Possible Mechanisms
Light to moderate alcohol consumption is associated with a reduced risk for cardiovascular diseases. Epidemiologic studies, like our analysis of the European Prospective Investigation into Cancer and ...
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Henk F.J. Hendriks
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S40-S42
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Moderate Alcohol Consumption and Risk of Developing Dementia in the Elderly: The Contribution of Prospective Studies
Moderate alcohol consumption, after controlling for potential confounding factors, has been found to be associated with a lower risk of developing dementia in several prospective epidemiological studi...
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Luc Letenneur
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S43-S45
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Moderate Alcohol Consumption and Cancer
Alcohol consumption may increase the risk for at least six types of cancer, although the evidence is not uniformly strong. Alcohol is not a carcinogen in standard tests but is likely a cocarcinogen, a...
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Klim McPherson
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S46-S48
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Moderate Drinking, Inflammation, and Liver Disease
It is well known that heavy drinking increases the risk of alcohol-related liver disease (ALD). Female gender, hepatitis C or B, obesity, and other cofactors increase susceptibility to ALD, so “safe” ...
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Gyongyi Szabo
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S49-S54
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Investigating the Association Between Moderate Drinking and Mental Health
In an attempt to relate “moderate drinking” to “mental health,” inadequacies of definition for both terms become apparent. Moderate drinking can be variously defined by a certain number of drinks to “...
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Nady El-Guebaly
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S55-S62
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Alcohol Drinking and Total Mortality Risk
To evaluate further the relation between alcohol consumption and total mortality, we have carried out new Cox proportional hazards model analyses of 21,535 deaths through 2002 in the Kaiser Permanente...
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Arthur L. Klatsky,
Natalia Udaltsova
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S63-S67
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Panel Discussion II: Net Effects of Moderate Alcohol Consumption on Health
This discussion focused on the effects of moderate alcohol consumption on conditions other than cardiovascular diseases and on total mortality. The panel was chaired by Richard Smallwood, and the pane...
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S68-S70
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| III. Influences at the Population Level |
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Why We Don't Know More about the Social Benefits of Moderate Drinking
The scientific literature about drinking shows that a preoccupation with the harms that occasionally befall those who drink too much or too fast is coupled with a virtual ignorance (in both senses of ...
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Dwight B. Heath
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S71-S74
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Patterns of Alcohol Consumption and Cardiovascular Risk in Northern Ireland and France
The PRIME Study was begun in 1991 and recruited 10,600 men aged 50 to 59 years in the WHO MONICA Project centers of Belfast, Lille, Strasbourg and Toulouse. Although drinkers in France and Northern Ir...
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Alun Evans,
Pedro Marques-Vidal,
Pierre Ducimetière,
Michele Montaye,
Dominique Arveiler,
Annie Bingham,
Jean-Bernard Ruidavets,
Phillipe Amouyel,
Bernadette Haas,
John Yarnell,
Jean Ferrières,
Frederic Fumeron,
Gerald Luc,
Frank Kee,
Francois Cambien
et al.
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S75-S80
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Harm, Benefits, and Net Effects on Mortality of Moderate Drinking of Alcohol Among Adults in Canada in 2002
Alcohol is an important risk factor contributing to the burden of chronic diseases and injuries, but is also associated with some health benefits. This study estimates risks and benefits associated wi...
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Jürgen Rehm,
Jayadeep Patra,
Ben Taylor
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S81-S86
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Alcohol Use and Mental Health in Developing Countries
This paper provides an overview of mental health and alcohol use in developing countries. The review shows that mental disorders are common and pose a significant burden on the health of developing na...
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Vikram Patel
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S87-S92
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Panel Discussion III: Moderation, Culture, and Risk
This discussion centered around the role of cultural influences on drinking and on the benefits and harms associated with moderate drinking. The panel was chaired by Morten Grønbæk and the panelists w...
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S93-S94
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| IV. Implications for Future Research |
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Panel Discussion IV: Implications for Future Research
This discussion focused on the implications of the available evidence on the benefits and risks of moderate drinking for future research. The panel was chaired by Eric Rimm and panelists were Francois...
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S95-S97
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| V. The Message on Moderate Drinking |
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Communicating Through Government Agencies
A comparison of worldwide recommendations on alcohol consumption reveals wide disparity among countries. This could imply that many of the recommendations do not adequately accommodate the science, gi...
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Richard Harding,
Creina S. Stockley
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S98-S102
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Communicating with the Public: Dilemmas of a Chief Medical Officer
Chief Medical Officers, or others directly responsible for the health of a population, have difficulty in dealing with alcohol. They must decide where to draw the line to minimize harm, as there is no...
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Richard Smallwood
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S103-S107
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The Influence of Print Media on their Readers' Understanding of the Benefits of Moderate Drinking∗
Journalism reflects and reinforces popular opinion. It is from the circulation that the owner's dividends and the journalists' salaries are derived, and journalists are constantly reminded of this. Al...
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Thomas Stuttaford
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S108-S109
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Panel Discussion V: The Message on Moderate Drinking
This discussion focused on the benefits and risks of moderate drinking in terms of communications to the public, through governmental regulations, official guidelines, the press, and advice to individ...
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S110-S111
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Alcohol and Pleasure∗
Curt Ellison asked me to speak on the subject of pleasure because he heard me discuss my book, The Pursuit of Pleasure, which appeared in l992 . I wrote the book in part to emphasize that an evolution...
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Lionel Tiger
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S112-S113
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| Closing Remarks |
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Closing Remarks
What do we know today about the risks and benefits of moderate alcohol consumption? While all may not agree, I believe that, for most people for whom alcohol is not contraindicated by health, ethical,...
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R. Curtis Ellison
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S114-S115
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| Frontmatter |
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Table of Contents
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A2-A3
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Masthead
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A4
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